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Symbol
Name
ID
Dlg3
discs large MAGUK scaffold protein 3
MGI:1888986
Phenotype annotations related to nervous system
Darker colors indicate more annotations
Human Phenotypes
Delayed speech and language development
Attention deficit hyperactivity disorder
Intellectual disability
Global developmental delay
Motor delay
Seizure
Disease(s) Associated with DLG3
non-syndromic X-linked intellectual disability 90

Mouse Phenotypes
abnormal brain morphology
abnormal forebrain development
abnormal neocortex size
abnormal somatosensory cortex morphology
abnormal barrel cortex morphology
abnormal innervation
abnormal axon morphology
abnormal synapse morphology
decreased excitatory postsynaptic current amplitude
prolonged excitatory postsynaptic current decay time
abnormal long-term potentiation
Availability Mouse Genotype
Dlg3Gt(P038A02)Wrst/Y
Dlg3tm1Grnt/Y

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory